Biochem/physiol Actions

Target IC₅₀: 1.4 µM against phosphatidylinositol 3-kinase

Reversible: yes

Product competes with ATP.

Primary Targetphosphatidylinositol 3-kinase

Cell permeable: yes

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Dittman, A., et al. 2013. ACS Chem. Biol.9, 495.Baumann, P., and West, S.C. 1998. Proc. Natl. Acad. Sci. USA95, 14066.Cardone, M.H., et al. 1998. Science282, 1318.Vlahos, C.J., et al. 1995. J. Immunol.154, 2413.Yano, H., et al. 1995. Biochem. J.312, 145.Vlahos, C.J., et al. 1994. J. Biol. Chem.269, 5241.Selected CitationsLee, J., et al. 2009. Cell Stem Cell5, 76.

Packaging

1 mg in Plastic ampoule

Packaged under inert gas

Physical form

A 10 mM (1 mg/325 µl) solution of LY 294002 (Cat. No. 440202) in DMSO.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Warning

Toxicity: Irritant (B)